College of Animal Biotechnology
Know About the College
The 'College of Animal Biotechnology' is a constituent college of the 'Guru Angad Dev Veterinary and Animal Sciences University' and is situated on the main campus of the University at Ludhiana. The erstwhile 'Post-Graduate Institute of Veterinary Education and Research (PGIVER)' was upgraded to 'School of Animal Biotechnology' in 2010. The school was further upgraded to the existing 'College of Animal Biotechnology' in 2019 with an objective to focus on research and teaching programs. The college aims towards directing the research to the needs of the farmers in the field of animal sciences by promoting translational research in the area of genomics, proteomics, bioinformatics, vaccinology, diagnostics, molecular biology, stem and cell biology.
The college offers a graduate program B.Tech. (Biotechnology) with 30 seats and post graduate programs viz. M.V.Sc. (Animal Biotechnology) / M.Sc. (Biotechnology) and 'M.Sc. (Biotechnology) with specialization in Animal Biotechnology' with a total of 17 seats and Ph.D. (Animal Biotechnology)/ Ph.D. (Biotechnology) with an intake capacity of 4 seats for students with bachelor degree in Biotechnology/Medical/Life Sciences/Biochemistry/Microbiology/Molecular Genetics/ B.F.Sc. The duration of the graduate program is for 4 years; the Masters program for 2 years, and the Ph.D. program for 3 years.
The college is also striving to conduct translational research in the various fields of biotechnology having direct or indirect implications on animals, particularly livestock. The college harbors numerous laboratories which are well equipped with sophisticated equipment to work in various fields of biotechnology and life sciences.
Mandate
- To undertake teaching, research, and training/extension in various facets of animal biotechnology, genomics, bioinformatics, microbial and environmental biotechnology.
- To generate scientific expertise and human resources trained for catering to institutional / industrial research and development requirements.
- To develop specialized and state-of-the-art laboratory facilities for research in the cutting-edge areas of biotechnology relevant to veterinary and allied sciences.
- To identify and characterize genes implicated in growth, production, reproduction, as well as stress and diseases.
- Harnessing omics and computational biotechnology in genetic improvement of farm animals.
- Development of molecular and serological diagnostics including point-of-care tests (POCTs), and new generation vaccines.
- To utilize stem and cell biology for enhancing lactation performance and regenerative therapy.
Goals
- To develop rapid point-of-care (POC) diagnostics with improved sensitivity and specificity for detection of infectious and non-infectious diseases.
- To develop improved, multi-component vaccines for economically important diseases of animals.
- To identify genome-wide markers for early and accurate selection for economically important traits, disease resistance, and parentage determination of animals.
- To facilitate research on stem cells for regenerative therapy in livestock.
- To develop and disseminate artificial intelligence and IoT driven, farmer-friendly technologies for smart data recording and precision farming.
Dean, College of Animal Biotechnology
Dr. Suresh Kumar Sharma
Address: Dean, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana
Email: deancoabt@gadvasu.in
Call: +91-161-2553356, 2553357
Brief Introduction
Dr. Suresh Kumar Sharma, took the additional charge of Dean, College of Animal BioTechnology at Guru Angad Dev Veterinary & Animal Sciences University, Ludhiana.
Former Dean/ Directors
|
S. No. |
Name |
Duration on the post |
Date of Retirement |
Photograph |
|
1. |
Dr. G.S. Brah |
01-02-2012 to 30-11-2013 As Director, School of Animal Biotechnology |
30-11-2013 |
|
|
2. |
Dr. Ramneek |
03-12-2013 to 06-10-2020 As Director, School of Animal Biotechnology |
--- |
|
|
3. |
Dr. YS Malik |
07-10-2020 to 15-04-2024 As Director, School of Animal Biotechnology |
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|
Academic Facilities
- The College of Animal Biotechnology has five lecture halls equipped well with modern audio-visual teaching aids including LED projectors, computer podiums, and smart displays.
- The college also has one committee room with a seating capacity for 40+ individuals, well equipped with up-to-date presentation facilities with video conferencing, broadband connectivity, air conditioning, and furnishing.
- The college has one mini-auditorium with a sitting capacity for 100+ individuals, well equipped with up-to-date presentation facilities with broadband connectivity, air conditioning, and furnishing.
- The college also has one library which has books (paperback/hardcover >354 and e-Books >22), meeting the requirements of UG, PG and Ph.D students. The thesis of the students of college are available in the college library.
Research Facilities
The College of Animal Biotechnology has the following laboratories:
- Molecular Diagnostics and Vaccinology Laboratory
- Cell and Molecular Biology Laboratory
- Animal Stem Cells Laboratory
- Leptospira Laboratory
- Animal Genomics Laboratory
- Proteomics and Metabolomics Laboratory
- Centralized Research Laboratory
Some of the specialized equipments in laboratories
Real Time PCR
PCR Thermocycler
NanoDrop One
Plate Reader and Hybrid Plate reader with Chemilumiuscence
Dark Field Microscope
Inverted Microscope with Imaging System and Fluorescent Assembly
Gel Documentation systems
Refrigerated Centrifuge
Micro Ultracentrifuge
Rotary-Microtome with dispensing system
Bio Safety Cabinets (Class III --01, Class-II--04)
Bio Safety Lab (Class II)
Cryo-preservation and multiple Deep Freezing (-80ºC & -20ºC) Facilities
Millipore Water Purification System
Incubators BOD/ CO2
High Performance Work Station for data analysis
Programmable Strip Cutter
ClassII Type B2 Biosafety Cabinet
Oxford Nanopore Minion Sequencer:
Gel Documentation System (Syngene)
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Veriti 96-well PCR Machine (Applied Biosystems Inc.)
Refrigerated Centrifuge (Thermo Scientific)
Upright Microscope with Imaging System
Faculty Detail
Dr. Ratan Kumar Choudhary
Designation : Assistant Professor
Contact Address : Department of Bioinformatics, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004
Telephone :
Mobile : +918427405856
Email : ratanchoudhary@gadvasu.in, vetdrrkc@gmail.com
Academic Credentials
- B.V.Sc. & A.H (TANUVAS, Chennai, India)
- M.V.Sc. (in AGB, IVRI, Bareilly India)
- Ph.D. (in Animal and Avian Sciences, University of Maryland, College Park, USA)
- Post-doctorate Fellow (University of Kentucky, Lexington, USA, 2011-2013)
- Post-doctorate Associate (University of Vermont, Burlington, USA, 2018-2020)
Teaching appointments
Field of Specialization: Stem cell and Molecular biology, Bioinformatics
Teaching various UG and PG courses of College of Animal Biotechnology pertaining to Cell and Molecular Biology, Bioinformatics and Animal Biotechnology.
Other appointments
- Member, PME cell (COABT)
- Member, IPR cell (COABT)
- Member sec. Budget, purchase/physical verification committee, COABT
- Store in charge- COABT
Area of research
Our laboratory, Animal Stem Cells lab, is working on two aspects of stem cell biology,
1) Exploring strategies to increase milk production in dairy animals by increasing mammary stem cell population using nucleotide analog, to increase cell turnover and lactation persistency
2) Developing regenerative therapy in canines using mesenchymal stem cell and cell-derived products. One of the approaches that we are interested in is the in-situ amelioration of mammary stem/progenitor cells. We are attempting to establish the application of stem cells and cell-based products for therapeutic application in animal diseases namely, mastitis, and wound healing. Finding an alternative therapy of mastitis without the use of antimicrobials and enhancing tissue regeneration using cell-based therapy are our long-term goals of the research.
Ongoing projects
| SN | Name/ No of Project/ Scheme | Funding agency | Period From To | Scientists involved (PI/ Co-PI) | Total Funding |
| 1. | Investigating the Role of Adipose Tissue-Derived Stromal Vascular Fractions (SVFs) Combined with Xanthosine in Veterinary Regenerative Medicine | DBT | 2022-2025 | PI: Dr. Ratan Kumar Choudhary CoPI; Dr. Yashpal Singh Dr. Ashwani Kumar | 49.99 Lakh |
| 2. | Immunomodulation potentials of apoptotic mesenchymal stem cells | SERB-SURE | 26-12-2023-26-12-2025 | PI: Dr. Ratan Kumar Choudhary | 23.56 Lakh |
| 3. | Modelling of indigenous diagnostics and immunopotent vaccine candidates to combat African swine fever in India | DBT | 25/03/2021- 25/03/2024 | PI: Yashpal S Malik Co-PI: Dr. Ratan Kumar Choudhary Dr. BV Sunil Kumar Dr. Niraj Singh | 39.56 Lakh |
Completed Projects
|
SN |
Name/ No of Project/ Scheme |
Funding Agency |
Period From To |
Total Funding |
Scientist involved (PI/ Co-PI) |
|
1.
|
Elucidating the role
of Cas6, Cas7 and Cas8 in spirochetes CRISPR adaptive immunity against alien
genetic elements |
DBT-
NER, New Delhi |
2017-2021 |
26.0 Lakhs (released 13 Lakhs) |
PI: IIT Guwahati CCPI from GADVASU Dr. Ratan Kumar Choudhary CoPI from GADVASU: Dr.
Satparkash Singh |
|
2.
|
Fast clotting
clinical grade hemostatic agent for emergency care |
DST-SERB |
2018-2022 |
-- |
PI and other centers CoPI NIT Rourkela
Co-PI from GADVASU: Dr. Ratan Kumar Choudhary Dr. Devendra Pathak |
Research honours awards
- Guru Angad Dev Veterinary and Animal Sciences University “Appreciation Award for Research” for brining extra-mural funds for the basic research to the university – 2018.
- Poster award at International Conference of Society for Bioinformatics and Biological Sciences (SBBS), SKAUST, Jammu, India; October 12-13.
- Winner of Vector Lab’s (USA) photomicrography contest – 2017 (https://vectorlabs.com/uk/gallery/contest.html)
- Poster Award at International Conference on Reproductive Health with Emphasis on Strategies for Infertility, Assisted Reproduction and Family Planning (ISSRF-2017), AIIMS, New Delhi, Jan 23-25 2017.
- International Travel Award by DST, New Delhi – 2015
- Second Prize Winner at BARC poster day at United States Department of Agriculture (USDA), Beltsville, Maryland- 2012
- First Prize Winner PhD Division at the Joint Annual Meeting of the American Dairy Science Association (ADSA) and American Animal Science Association (ASAS) at New Orleans- 2011
- Novus International Inc. Travel Award to 63rd Annual EAAP meeting at Bratislava, Slovakia– 2011
- Second Prize Winner of Oral presentation, University of Maryland- 2011
- Third Prize Winner at BARC poster day USDA, Beltsville-2011
- R. F. Davis Scholarship for outstanding academic record, research and commitment to agriculture and natural resources, University of Maryland – 2011
- Dean’s Fellowship, University of Maryland, College Park, Maryland – 2011
- First Prize Winner of poster presentation, University of Maryland, College Park-2011
- J. K. Goldhaber Travel Award, University of Maryland- 2010
- Guru Angad Dev Veterinary and Animal Sciences University “Appreciation Award for Research” for brining extra-mural funds for the basic research to the university – 2018.
- Poster award at International Conference of Society for Bioinformatics and Biological Sciences (SBBS), SKAUST, Jammu, India; October 12-13.
- Winner of Vector Lab’s (USA) photomicrography contest – 2017 (https://vectorlabs.com/uk/gallery/contest.html)
- 2017 Poster Award at International Conference on Reproductive Health with Emphasis on Strategies for Infertility, Assisted Reproduction and Family Planning (ISSRF-2017), AIIMS, New Delhi, Jan 23-25 2017.
- International Travel Award by DST, New Delhi – 2015
- Second Prize Winner at BARC poster day at United States Department of Agriculture (USDA), Beltsville, Maryland- 2012
- First Prize Winner PhD Division at the Joint Annual Meeting of the American Dairy Science Association (ADSA) and American Animal Science Association (ASAS) at New Orleans- 2011
- Novus International Inc. Travel Award to 63rd Annual EAAP meeting at Bratislava, Slovakia– 2011
- Second Prize Winner of Oral presentation, University of Maryland- 2011
- Third Prize Winner at BARC poster day USDA, Beltsville-2011
- R. F. Davis Scholarship for outstanding academic record, research and commitment to agriculture and natural resources, University of Maryland – 2011
- Dean’s Fellowship, University of Maryland, College Park, Maryland – 2011
- First Prize Winner of poster presentation, University of Maryland, College Park-2011
- J. K. Goldhaber Travel Award, University of Maryland- 2010
No of publications
| Research: 59 | Extension: 06 | Books: 06 | Manuals: 08 Book Chapter:08 |
|---|
Publication
- Sahoo B, Choudhary, R. K., Sharma P, Choudhary S and Gupta MK. 2021. Significance and Relevance of Spermatozoal RNAs to Male Fertility in Livestock. Frontiers in Genetics. 12:768196. (IF-4.599).
- Choudhary, R. K and Zhao, F-Q. 2022. Invited Review: Stem cells in mammary health and milk production. Current Stem Cell Research and Therapy. 17(3):207-213 (IF-3.758)
- Choudhary, R. K. and Capuco, A. V. 2021. Expression of NR5A2, NUP153, HNF4A, USP15 and FNDC3B is consistent with their use as novel biomarkers for mammary stem/progenitor cells. Molecular Histology. 52(2):289-300. (IF-2.35).
- Spitzer, A., Tian, Q., Choudhary, R. K. and Zhao, F-Q. 2020. Bacterial endotoxin induces oxidative stress and reduces milk protein expression and hypoxia in the mammary gland. Oxidative Medicine and Cellular Longevity. 24;2020: 3894309. (IF-4.868).
- Shangraw, E., Rodrigues, R., Witzke, M., Linder, H. F., Choudhary, R. K., Spitzer, A., Zhao, F.-Q., McFadden, T. B. 2020. Intramammary lipopolysaccharide infusion elicits local or systemic effects depending on milk component. Journal of Dairy Science. 103(8):7487-7497. (IF-4.034)
- Capuco, A. V. and Choudhary, R. K. 2020. Invited Review: Determinants of milk production: Understanding population dynamics in the bovine mammary epithelium. Journal of Dairy Science. 103(3):2928-2940. (IF-4.034)
- Choudhary R. K., Choudhary, S., Mukhopadhyay, C. S., Pathak, D. and Verma, R. 2019. Deciphering the transcriptome of prepubertal buffalo mammary glands using RNA sequencing. Functional & Integrative Genomics. 19(2):349-362. (IF-3.41)
- Choudhary, S., Li, W., Bickhart, D., Verma, R., Sethi, R. S., Mukhopadhyay, C. S. and Choudhary, R. K. 2018. Examination of the xanthosine response on gene expression of mammary epithelial cells using RNA-seq technology. Journal of Animal Science and Technology. 60:18. (IF-1.95)
- Choudhary, R. K., and Capuco, A. V. 2012. In vitro expansion of mammary stem/progenitor cell population by xanthosine treatment. BMC Molecular and Cell Biology. 13:14. (IF-2.81)
- Choudhary, R. K., Li, R. W., Evock-Clover, C. M. and Capuco, A. V. 2013. Comparison of transcriptomes of long-term label-retaining-cells and control cells microdissected from mammary epithelium: An initial study to characterize potential stem/progenitor cells and identify possible biomarkers. Frontiers in Oncology. 3 (21). (IF-6.244)
Authored/Edited Books:
- Choudhary, R. K. and Choudhary, S. 2021. Stem Cells in Veterinary Science. Hard Cover ISBN: 978-981-16-3463-5. Pp. XII, 375. (editor) https://link.springer.com/book/10.1007/978-981-16-3464-2?page=1#toc
- Mukhopadhyay, C. S., Choudhary, R. K. and Iquebal, M. A. 2017. Basic Applied Bioinformatics, Wiley. ISBN: 978-1-119-24433-2. (editor) https://www.wiley.com/en-us/Basic+Applied+Bioinformatics-p-9781119244332
- Choudhary R. K and Malik Y S. 2021. Biotechnological Approaches in Animal Research and Disease Diagnosis. College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University Ludhiana, Punjab. ISBN 978-93-5566-112-8. Pp. 106- (editor)
- Malik, Y. P. S., Sethi, R. S. Deepti, N., Choudhary, R. K., Pathak, D., Mehta, N. and Shanthanagouda, A. H. (2022). Transforming Livestock Economy through Innovations in Immunology and Biotechnology: A Souvenir-cum-Compendium. College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University Ludhiana, Punjab. ISBN 978-93-5619-958-3. Pp. 250.- (editor).