Veterinary Physiology & Biochemistry

With the inception of the College of Veterinary Science in November 1969 under Punjab Agricultural University, the Department of Veterinary Physiology was created with one Assistant Professor and one Professor. Gradually the facilities in terms of Laboratory space, equipment, etc. were procured and other infrastructure was developed, for teaching, research and extension programmes. After the establishment of Guru Angad Dev Veterinary & Animal sciences University, the Department of Veterinary Biochemistry was merged with this department in 2009 as per the guidelines of Minimum Standards of Veterinary Education of VCI and is now exist as Department of Veterinary Physiology and Biochemistry.

Presently, the department has well-qualified four Physiologists and three Biochemists to impart high standards of education to undergraduate and postgraduate students in Veterinary Physiology and Biochemistry under the dynamic leadership of Dr. Digvijay Singh, Professor & Head of the Department. The department offers a 4+1 credit hour course of Veterinary Physiology to the First Professional B.V.Sc. & A.H. students and 2+1 credit course of Veterinary Biochemistry to the Second Professional B.V.Sc. & A.H. students. Apart from this, the faculty of the department is also involved in teaching the Diagnostic Laboratory practices of Veterinary Clinical Practices (VCP-II) course (0+6 credit hours) offered to the Fourth Professional B.V.Sc. & A.H. students.

The prime mandate of the Department is to train the undergraduate students in the field of Veterinary Physiology and Biochemistry for subsequently making them competent Veterinarians and to provide advance training/education to the postgraduate students in various aspects of Veterinary Physiology and Biochemistry. The Department is equipped with Fully Automatic Wet Biochemistry Analyzer, Semi-automatic Biochemistry Analyzer, PCR, Gel Documentation System etc. for carrying

out the research on the physiological and biochemical aspects of animal health and production, and is extending these facilities to other departments of the University. The major thrust areas of the department is to work on physiological/biochemical markers in relation to animal health and production, physiology of rumen ecosystem & clinical applications of stem cells.

Email: officevpb@gmail.com

Ph. No. 0161-2414034


Goals


  • To carry out the research in the thrust areas and professional upliftment of Veterinarians through imparting education at undergraduate and postgraduate levels and by updating them with the applicable research findings and conclusions arrived at from the research of the department.

Thrust Area


  • Physiology of stress and understanding the mechanisms to cope with stress.
  • Physiological and environmental factors affecting growth and production in farm animals.
  • Physiological/Biochemical markers in relation to animal health and production.
  • Physiology of rumen ecosystem.
  • Clinical applications of stem cells.

Veterinary Physiology & Biochemistry


Dr. Chanchal Singh

Address: Department of Veterinary Physiology & Biochemistry, College of Veterinary Science, Guru Angad Dev Veterinary & Animal Sciences University, Ludhiana 141004

Email: chanchalsingh@gadvasu.in, drchanchal833@gmail.com

Call: 0161- 2414034 (O)

Fax: +91-161-2400822

Brief Introduction :

Dr. Chanchal Singh, Professor(Veterinary Biochemistry) in the Department of Veterinary Physiology and Biochemistry at the College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana has over sixteen years of teaching expertise in Veterinary Biochemistry. He completed his graduation from the West Bengal University of Animal and Fisheries Sciences, Kolkata, earning MVSc. and Ph.D. degrees from IVRI, Izatnagar. He's guided four postgraduates and one doctoral student while serving as Co-advisor to over 30 others. He has led an extramural project funded by SERB, DST and contributed to other extra mural projects as Principal and Co-Principal Investigator, respectively. His publication history comprises over 60 national and international research papers, book chapters, extension articles, and practical manuals. He has delivered expert lectures in CAFT and other trainings .He's contributed as a visiting faculty for International training at the University of Newcastle, Australia. He has garnered 14 prestigious awards for his research presentation sat national conferences. He has been actively involved in various departmental, college, university level committees .Additionally, he is executive member of three professional societies.

Faculty Detail

Dr. Digvijay Singh

Designation : Professor

Contact Address : Department of Veterinary Physiology & Biochemistry, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab 141004.

Telephone : 0161-2414034

Mobile : +91-9417476565

Email : digvijay231@gmail.com, officevpb@gmail.com

Academic Credentials

  • B.V. Sc. & A.H. COVS, Punjab Agricultural University, Ludhiana
  • M.V. Sc. (Vety. Physiology) COVS, Punjab Agricultural University, Ludhiana
  • Ph.D. (Vety Physiology) COVS, Punjab Agricultural University, Ludhiana

Teaching appointments

  • I am actively involved in undergraduate and post graduate teaching since joining this department of Veterinary Physiology in erstwhile Punjab Agricultural University, Ludhiana. Cardiovascular, digestive, growth, climatology and endocrinology & lactation physiology has been the areas of my teaching till now. I have prepared the teaching manuals for cardiovascular, digestive physiology and climatology besides being actively involved in preparation of videos of the practicals of Veterinary Physiology which are displayed on University YouTube channel.

Other appointments

  • Held the charge of University Librarian from 01.04.2021 to 27.05.2022.
  • Chief Warden from 04.08.2020 till 23.04.2021.
  • Warden Hostel No.9 from 17.05.2017 till 23.04.2021.
  • Joined as Dean, College of Veterinary Science, Rampura Phul on 31.10.2024

    Area of research

    • The areas of my research interest include Cardiovascular and digestive physiology. I have guided eight postgraduate students who have successfully submitted their dissertations on Studies on  physiological profiles of Flunixin Meglumine and Dexamethasone administration during Endotoxic shock in buffalo calves, Studies on physiological effects of flunixin meglumine, dextran-40 and whole blood in various combinations in endotoxemic buffalo calves and Physio-pathological studies on induced endotoxemia in buffalo calves respectively and on various aspects of digestive physiology. Besides that I have successfully completed a research project entitled “Effect of Herbal formulation on digestibility and nutrient utilization of wheat straw in buffalo calves” financed by AYURVET, BADDI (HP). The significant findings from my research are:  
    •  The treatment combination of Hypertonic Saline Solution @ 4ml/Kg bw + Plasmex-D-40 @ 10 ml/Kg bw +Flunixin meglumine@ 1.1 mg/Kg bw + blood @ 20ml / kg bw was found to be the best out of all the combinations tried.
    • Hypertonic saline, Flunixin meglumine @ 1.1mg/Kg bw and Dexamethasone @ 4mg/Kg bw in different combinations effectively restore the various hemodynamic parameters to normal pre-infusion values and that these treatment combinations can be used as immediate resuscitation measure to provide the clinician valuable time to plan further long term treatment.
    • Out of all the drugs used, Flunixin meglumine @ 1.1 mg/ kg bw was found to be the most efficient. While the survival time of all the animals was considerably prolonged as a result of these treatments, no additional or specific advantage was observed by the use of steroid dexamethasone in the treatment of endotoxemic buffalo calves.
    • On the basis of the increase in the BW of the animals, diet intake, other ruminal profiles and digestibility, it was concluded that the drugs AV/DAC-16 and SDS-12 improve the digestibility and nutrient utilization of the diet fed to the animals of which wheat straw constituted a major component.
    • UMMB supplementation causes increase in population of ruminal microflora and levels of rumen metabolites which in turn improve the nutrient utilization. Therefore, it is recommended that during the lean period or dry summer season when there is shortage of green fodder, UMMB should be supplemented with wheat straw in order to maintain optimum microbial fermentation in the rumen for proper health and growth of animals at the low cost of feeding.
    • Feeding Yea Sacc 1026 along with wheat straw helps in improvement of nutrient utilization of poor quality roughages and helps in body weight gain by increasing the population of ruminal microflora and levels of rumen metabolites.It is recommended to supplement Yea Sacc 1026 with poor quality roughages during the lean periods in order to optimize the rumen ecosystem for better performance of animals.

    Research honours awards

    • D V Singh 2023 “Veterinary Physiology Vis-a-Vis Veterinary Extension.” Lead paper on importance & usage of Veterinary Physiology as a discipline in farm/field were communicated to delegates and farmers at 5 th National conference of Society for Veterinary & Animal Husbandry Extension (SVAHE) on Smart livestock extension for enhancing farmers’ income-An extension bounty held from October 12-14, 2023 at KCVAS, Amritsar, Punjab. 
    • BEST POSTER PRESENTATION AWARD at XXVI Annual Conference of Society of Animal Physiologists of India on “Physiological Innovations to Forecast the Impact of Climate change and to Evolve Strategies for Sustainable Livestock Production" on 21-22nd December,2017 held in dept. of Vety. Physiology & Biochemistry, COVS, KVAFSU, Bidar, Karnataka.
    • D. N. Mullick memorial award presented at XXII annual conference of SAPI held at DUVASU, Mathura from Nov. 19-21, 2013.
    • BEST POSTER PRESENTATION AWARD at 12th Punjab Science Congress held on Feb. 7-9, 2009 at College of Basic Sciences, P.A.U. Ludhiana
    • BHARAT JYOTI AWARD from India International Friendship Society, New Delhi on 23 rd June, 2006 for meritorious services, outstanding performance and remarkable role in my field.
    • BEST POSTER PRESENTATION AWARD at VIII annual conference of Indian Association for the Advancement of Veterinary Research & National Symposium and Indian Veterinary Congress held on Feb. 22-23, 2001 at College of Veterinary Science, P.A.U. Ludhiana.
    • Appreciation letter from AYURVET
    • Appreciation letter from Organizing secretary, 28th annual conference and international symposium of Society of Toxicology (STOX) held on Oct. 16-18, 2008
    • Appreciation letter from Organizing secretary, 26th annual conference of IAVP international symposium and C.L. Davis Satellite Seminar held on Oct. 28-30,2009.

    No of publications

    Research: 71Extension: 06     Books: Nil     Review Articles: 03

    Publication

    • Anirudh Mittal, Manjinder Sharma and Digvijay Singh 2023 A study on alterations in physio- biochemical parameters of Ascites in dogs.Accepted for publication in Haryana Veterinerian
    • Kaur N, Sharma M, Lonare MK and Singh DV, 2020 Cytoprotective Potential of curcumin and resveratrol during freeze-thaw cycle of buffalo bone marrow derived mesenchymal stem cells. Ruminant Science, 9 (2):215-222 (NAAS Rating: 5.47). 
    • Kaur N, Sharma M, Lonare MK and Singh DV, 2020 Bioantioxidants protect the buffalo bone marrow derived mesenchymal stemm cells against oxidative stress induced during freeze-thaw cycle. Toxicology International, 28 (1):17-30 (NAAS Rating: 5.23).
    • Faheem Sultan, Rajdeep Kaur, Arshad Hussain Mir, Ishfaq Maqbool, Milindmitra Lonare, Digvijay Singh, Satyavan Rampal, Javeed Ahmad Dar 2020 Rosuvastatin and retinoic acid may act as ‘pleiotropic agents’ against ?- adrenergic agonist-induced acute myocardial injury through modulation of multiple signalling pathways. Chemico- Biological Interactions 318: 1-12 (NAAS Rating:9.723).
    • Irtiza Nabi, D V Singh & N. K. Sood 2019 A comparative evaluation of different treatment regimens in endotoxemic buffalo calves – A Physio-pathological perspective. Journal of Biomedical Science and Engineering (JBiSE) 12(4) : 119-125. (NAAS rating 6.7). 
    • J P Singh and D V Singh 2018 Cardiovascular haemodynamics and some biochemical profiles of endotoxemic buffalo calves on infusion of HSS, Flunixin meglumine & Blood. Journal of Biomedical Science and Engineering (JBiSE) 11(6) : 119-125. (NAAS rating 6.7). 
    • Somya Rao and D V Singh 2015 Impact of UMMB supplementation on rumen microbiology in buffalo calves (Bubalus bubalis). Indian Veterinary Journal 92 (8) : 34-36 . (NAAS Rating: 4.42)
    • S.P. Singh & D.V. Singh 2014 Impact of YeaSacc 1026 supplementation to exclusive wheat straw feeding on rumen microflora in buffalo calves. Haryana Veterinerian 53 (2) 148-150. (NAAS Rating: 5.36)
    • Irtiza Nabi, Digvijay Singh, Naresh Kumar Sood (2013).Physiopathology induced endotoxaemia in bovine and its treatment regimen. Journal of Biomedical Science and Engineering, 2013 6, 1077-1084 (NAAS rating 6.7).
    • D. V. Singh and H. Bhatia 2012 Effect of herbal formulation AV/ DAC-16 supplementation on ruminal profiles in buffalo calves (Bubalus bubalis). Journal of Buffalo Science 1(1) : 27-31
    • D.V. Singh, S.K. Bansal and G.S.Ghumman 2011 Effect of flunixin meglumine alone and in combination on haemodynamics during bovine endotoxic shock and after treatment. J. Biomedical Science and Engineering, 2011, 4, 29-33 (NAAS rating 6.7).

    Veterinary Physiology & Biochemistry

    Former Faculty


    Sr. No. Name Designation Superannuation/ Transfer/ Promotion Photograph
    1. Dr. Rajvir Singh Professor 31-07-2006
    2. Dr. SPS Sangha Professor 30-09-2016
    3. Dr. Rajesh Jindal Professor 31-10-2020

    Veterinary Physiology & Biochemistry

    Sr. No.

    Title of Project

    Objectives

    Investigators

    Budget

    In lacs

    Sponsoring Agency (Rs.)

    Duration of the Project

    1.             

    Effect of Herbal formulation on digestibility and nutrient utilization of wheat straw in buffalo calves

    To know the efficacy of the two new drug combinations

    PI: Dr. Digvijay Singh

    1.75

    Ayurvet

    2006-07

    2.             

    Biochemical characterization of antimicrobial peptide genes in buffaloes in health and disease

    i) To find out nucleotide sequencing of various defensins present in buffalo myeloid and non myeloid tissues.

    ii) Designing peptides based on deduced amino acid sequencing from nucleotide sequencing.

    PI: Dr. Sandeep Kumar

     

    13.45

    DBT

    2008-09

    3.             

    Heavy metal exposure vis-à-vis reproductive performance in buffaloes

    To evaluate the relationship among heavy metal levels in fodder, water, hair, blood of the dairy animals and its influence on blood biochemical profile and ovarian steroid concentrations in relation to their reproductive performance.

    PI: Dr. Rajesh Jindal

    Co PI: Dr. Shashi Nayyar,

    6.818

     UGC-MRP

    2012-13

    4.             

    Studies on fibronectin binding outer membrane proteins of pasteurella multocida: role in extracellular matrix adhesion and pathogenesis in bubalus bubalis.

    To study interaction between buffalo fibronectin and Pastuerella multocida.

    PI: Dr. Chanchal Singh

    23.48

    DST (SERB)

    2013-16

    5.             

    Clinical application of bone marrow derived mesenchymal stem cells from buffalo for allogeneic and xenogeneic cutaneous regeneration of chronic wounds

    i) Isolation, culture expansion, characterization and cryopreservation of bone marrow derived MSCs from buffalo. 

    ii) Evaluation of bone marrow derived MSCs for allogeneic and xenogeneic cutaneous regeneration of chronic wounds in clinical cases.

    PI: Dr. Manjinder Sharma,

    Co PI: Drs. Digvijay Singh, Rahul Udihiya & Milindmitra Lonare

    14.70

    UGC-MRP

    2015-18

    Veterinary Physiology & Biochemistry

    • To carry out the research in the field of Endocrinology, Reproductive Physiology, Cardiovascular Physiology, Digestive Physiology, Mineral Physiology, Clinical Biochemistry and Molecular Biochemistry to subsequently improve the health and production of livestock.





    Veterinary Physiology & Biochemistry

    Extension Programmes

    • The faculty members of the department regularly deliver lectures in the training progammes for the young prospective dairy farmers organized by the Department of Extension Education, GADVASU, Ludhiana.
    • The faculty members publish popular articles for the benefit of farmers/veterinarians.

    Extension activities

    • The department participates actively in exhibition for Pashu Palan Mela of GADVASU.
    • The depratment is contributing significanctly through Clinical samples analysis in the Clinical Diagnostic Laboratory of the GADVASU Veterinary Clinics.

    Veterinary Physiology & Biochemistry

    Research : 261
    Extension : 08
    Books/Mannuals : 06

    Veterinary Physiology & Biochemistry

    The department has well equipped UG and PG laboratories with facilities forcarrying out research in the thrust areas. The department is also extendingthese facilities to other departments of the college. Major facilitiesavailable with the department are:

    • Well equipped Endocrinology lab. ELISA.
    • Cardiovascular Lab. with ECG,Polyphysiograph and facilities for haematology
    • Digestive Physiology lab. Atomic AbsorptionSpectrophotometer
    • Clinical Biochemistry lab. with ChemistryAnalyzer and Digital UV-visible Spectrophotometer
    • Molecular Biochemistry lab
    • GELDOC SYSTEM

    UG Biochemistry Laboratory

    UG Veterinary Physiology Laboratory

    PG Biochemistry Laboratory

    Digestive Physiology Laboratory

    Lecture Hall No. 3 (Front view)

    Veterinary Physiology Lecture Hall No.3 (Rear View)


    Veterinary Physiology & Biochemistry

    • Molecular Biochemistry laboratory
    • The department has a Clinical Biochemistry laboratory.

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